Endocrine Abstracts

Human seminal plasma contains a large array of proteins required for the normal physiology of spermatozoa and fertilization. To provide informations about the physiological mechanisms of male fertility we performed proteomic studies on human seminal plasma by a top-down approach. A semen sample was collected in a fertile normospermic man (sperm concentration 60×106 per ml; progressive motility 58%; normal morphology 45%). Hormonal blood assay was performed: tes...

The chemical composition of the cervical mucus (CM), its physical characteristics and the volume secreted show cyclical changes during the menstrual cycle.Clinical proteomics has recently developed new technologies and bioinformatics useful in identifying molecular markers of physiology and pathology. The development of novel mass spectrometers, like the LTQ-Orbitrap, considerably contributed to increase the quantity of acquired data. Aim of the present ...